Accelerating Biologics Manufacturing by Modeling: Process Integration of Precipitation in mAb Downstream Processing
نویسندگان
چکیده
منابع مشابه
PROTEIN A CHROMATOGRAPHY – THE PROCESS ECONOMICS DRIVER IN mAb MANUFACTURING
part of the pharmaceutical industry. The market for recombinant proteins exceeded $ 100 billion in 2011 with a contribution of 45% sales by monoclonal antibodies (mAbs) (1). The introduction of the first mAb biosimilars in Europe raised the competitive pressure in an increasingly crowded market place. The industry faces challenges, such as patent expirations accompanied by approvals of correspo...
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T he cell therapy industry (CTI) is poised to grow rapidly over the next decade, treating millions of patients and generating annual revenues into the tens of billions of US dollars (1, 2). To meet that high-growth demand, large CTI system manufacturers (e.g., Corning, Nunc/Nalgene, and GE Healthcare) and leading contract manufacturing organizations (CMOs, such as Lonza) are developing and inte...
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ژورنال
عنوان ژورنال: Processes
سال: 2020
ISSN: 2227-9717
DOI: 10.3390/pr8010058